Empirical assessment of effect of publication bias on meta-analyses
نویسندگان
چکیده
منابع مشابه
Empirical assessment of effect of publication bias on meta-analyses.
OBJECTIVE To assess the effect of publication bias on the results and conclusions of systematic reviews and meta-analyses. DESIGN Analysis of published meta-analyses by trim and fill method. STUDIES 48 reviews in Cochrane Database of Systematic Reviews that considered a binary endpoint and contained 10 or more individual studies. MAIN OUTCOME MEASURES Number of reviews with missing studie...
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INTRODUCTION Positive results have a greater chance of being published and outcomes that are statistically significant have a greater chance of being fully reported. One consequence of research underreporting is that it may influence the sample of studies that is available for a meta-analysis. Smaller studies are often characterized by larger effects in published meta-analyses, which can be pos...
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ژورنال
عنوان ژورنال: BMJ
سال: 2000
ISSN: 0959-8138
DOI: 10.1136/bmj.320.7249.1574